The U.S. Supreme Court’s decision in Alice v. CLS Bank from a decade ago has considerably influenced the landscape of patent eligibility. Over the past ten years, numerous patents have been deemed ineligible under the guidelines set forth by the landmark ruling. The ensuing years have seen various courts further clarifying and expanding the legal criteria for patent eligibility, shaping the direction of intellectual property law in significant ways. This retrospective highlights the most pivotal decisions in the realm of patent eligibility following the Alice ruling.